Project publications

Preclinical and Translational PET/MR Imaging.
Wehrl HF, Wiehr S, Divine MR, Gatidis S, Gullberg GT, Maier FC, Rolle AM, Schwenck J, Thaiss WM, Pichler BJ.
J Nucl Med. 2014 May 15;55(Supplement 2):11S-18S.

Breaking the mould - novel diagnostic and therapeutic strategies for invasive pulmonary aspergillosis in the immune deficient patient.
Thornton CR.
Expert Rev Clin Immunol. 2014 Jun;10(6):771-80

The impact of weakly bound 89Zr on preclinical studies: Non-specific accumulation in solid tumors and aspergillus infection.
Severin GW, Jørgensen JT, Wiehr S, Rolle AM, Hansen AE, Maurer A, Hasenberg M, Pichler B, Kjær A, Jensen AI.
Nucl Med Biol. 2015 Apr;42(4):360-368.

ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo.
Rolle AM, Hasenberg M, Thornton CR, Solouk-Saran D, Männ L, Weski J, Maurer A, Fischer E, Spycher PR, Schibli R, Boschetti F, Stegemann-Koniszewski S, Bruder D, Severin GW, Autenrieth SE, Krappmann S, Davies G, Pichler BJ, Gunzer M, Wiehr S.
Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):E1026-33. doi: 10.1073/pnas.1518836113.

New pathogen-specific immunoPET/MR tracer for molecular imaging of a systemic bacterial infection.
Wiehr S, Warnke P, Rolle AM, Schütz M, Oberhettinger P, Kohlhofer U, Quintanilla-Martinez L, Maurer A, Thornton C, Boschetti F, Reischl G, Autenrieth IB, Pichler BJ, Autenrieth SE.
2016 Mar 8;7(10):10990-1001. doi: 10.18632/oncotarget.7770. PubMed PMID: 26934329; PubMed Central PMCID: PMC4905453.

Optimized procedures for manganese-52: Production, separation and radiolabeling.
Fonslet J, Tietze S, Jensen AI, Graves SA, Severin GW.
Appl Radiat Isot. 2017 Mar;121:38-43. doi: 10.1016/j.apradiso.2016.11.021. Epub 2016 Dec 21.

Towards Translational ImmunoPET/MR Imaging of Invasive Pulmonary Aspergillosis: The Humanised Monoclonal Antibody JF5 Detects Aspergillus Lung Infections In Vivo.
Davies G, Rolle AM, Maurer A, Spycher PR, Schillinger C, Solouk-Saran D, Hasenberg M, Weski J, Fonslet J, Dubois A, Boschetti F, Denat F, Gunzer M, Eichner M, Ryder LS, Jensen M, Schibli R, Pichler BJ, Wiehr S, Thornton CR. Theranostics. 2017 Aug 11;7(14):3398-3414. doi: 10.7150/thno.20919. eCollection 2017.

Dual, Site-Specific Modification of Antibodies by Using Solid-Phase Immobilized Microbial Transglutaminase.
Spycher PR, Amann CA, Wehrmüller JE, Hurwitz DR, Kreis O, Messmer D, Ritler A, Küchler A, Blanc A, Béhé M, Walde P, Schibli R.
Chembiochem. 2017 Oct 5;18(19):1923-1927. doi: 10.1002/cbic.201700188. Epub 2017 Aug 29.

Neodymium-140 DOTA-LM3: Evaluation of an In Vivo Generator for PET with a Non-Internalizing Vector.
Severin GW, Kristensen LK, Nielsen CH, Fonslet J, Jensen AI, Frellsen AF, Jensen KM, Elema DR, Maecke H, Kjær A, Johnston K, Köster U.
Front Med (Lausanne). 2017 Jul 12;4:98. doi: 10.3389/fmed.2017.00098. eCollection 2017.